| Autor: |
Koen Theunissen, Steffen Fieuws, Liesbet Lammertijn, G. Bries, Helena Maes, Vincent Maertens, Pierre Zachee, Mariëlle Beckers, Inge Vrelust, Vibeke Vergote, Kristel Buvé, Kathy Goris, Hélène Schoemans, Beata Hodossy, Christine Schuermans, Fabienne Dobbels, Griet Huysmans, Stefaan Meers, Hilde Demuynck, Sabina De Geest, Johan Maertens |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Biology of Blood and Marrow Transplantation. 26:S354 |
| ISSN: |
1083-8791 |
| DOI: |
10.1016/j.bbmt.2019.12.181 |
| Popis: |
We performed a cross-sectional study to describe the survivorship profile of a convenience sample of 244 allogeneic hematopoietic cell transplantation (HCT) recipients based on a comprehensive health status model and we compared them to controls from the general Belgian population using the Health Interview Survey database (matched 1:3 based on age, gender and province of residence), a national assessment performed every five years since 1997 to evaluate the general health status of the population. Included patients were above age 18, at least 2 years post-HCT and presented to our center for a scheduled outpatient appointment. Patients hospitalized for a life-threatening condition, presenting with any other major illness (resulting in an expected survival of less than 6 months) or any major visual, hearing, cognitive or psychiatric conditions precluding consent were excluded. We performed a comprehensive evaluation including a medical evaluation and record review, a directed interview and a self-reported survey on the patient's physical, psychosocial and behavioral functioning using standardized instruments. Descriptive statistics and conditional logistic regressions were used as appropriate. 244 out of 300 eligible survivors (81% response rate) participated (median 8.4 years post HCT; IQR 7.9; range 2.3-24.4). The most prevalent issues noted were graft versus host disease (46.7%), impaired kidney function (63.9%), the presence of a metabolic syndrome (33.6%), medication non-adherence (for immunosuppressive medication: 60.4% implementation issues, 7.5% non-persistence issues; for other medication: 53.8% omission issues), low physical activity (54.5%) and inappropriate UV exposure (44.7%). Compared to the general population, survivors were significantly more likely to report a sub-optimal overall perceived health status (82.0% versus 52.1% respectively, OR 4.58 (3.08-6.80), p These findings point towards the complex care needs of HCT survivors and call for the implementation of chronic care models for follow-up care. We currently are planning an eHealth powered model of care intervention to address these issues. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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Full Text from ScienceDirect