Hemoglobinopatisi olan bir bebekte biliyer atrezi komplikasyonu olarak kandidemi

Autor: Maria Hatzistilianou, Athanasios Tragiannidis, Maria Palabougiouki, Ioannis Kyriakidis, N. Gombakis, Tatiani Moudiou, Eleni Vasileiou, Timoleon Vyzantiadis, Maria Stamou
Rok vydání: 2019
Předmět:
Zdroj: Türk Pediatri Arşivi.
ISSN: 1306-0015
DOI: 10.14744/turkpediatriars.2019.67674
Popis: Both biliary atresia and hemoglobinopathies have been associated with a higher incidence of bloodstream infections. We hereby present the case of a female infant of Nigerian descent with extrahepatic biliary atresia and double heterozygocity for sickle cell disease and alpha-thalassemia. Kasai hepatoportoenterostomy was performed in the child’s sixth week of life. Bloodstream infections occurred two months post-hepatoportoenterostomy, even though the infant was still in prophylactic antibiotic treatment: the first was due to Candida albicans and was followed by bacteremia due to Escherichia coli. A third infection, confined to the skin only, was due to Acinetobacter spp. Treatment options, predisposing factors, and the pathophysiology of bloodstream infections in patients with biliary atresia and aberrant hemoglobin are discussed herein.
Databáze: OpenAIRE