ChemInform Abstract: Synthesis and GABAAReceptor Activity of A-Homo Analogues of Neuroactive Steroids

Autor:	Pablo H. Di Chenna, Gerardo Burton, Hana Chodounska, Adriana Silvia Veleiro, Zdena Kristofikova, Maria Virginia Dansey, Alexander Kasal
Rok vydání:	2010
Předmět:	chemistry.chemical_classification chemistry.chemical_compound Neuroactive steroid Stereospecificity Ketone Diene GABAA receptor Chemistry Stereochemistry Cyclopropylcarbinol General Medicine Catalysis
Zdroj:	ChemInform. 41
ISSN:	0931-7597
Popis:	Key steps in the synthesis of title compounds, e.g. (VIII), are a microwave-assisted rearrangement of cyclopropylcarbinol (I) and a regio- and stereospecific β-epoxidation of diene (III) in the presence of a fructose-derived ketone as chiral catalyst.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b7205dc6438547323b2c1f63f437aeec https://doi.org/10.1002/chin.201042190 Zobrazit plný text záznamu Plný text