Evaluation of autologous and homologous platelet rich plasma as a surgical wound healing promoter in rabbits
| Autor: | Khizar Matloob, Asim Khalid Mahmood, Uzma Farid Durrani, Muhammad Shahid Tahir, Abid Hussain, Rashid Hussain, Raheela Akhtar, Beenish Zahid |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
030203 arthritis & rheumatology
0106 biological sciences Pathology medicine.medical_specialty General Veterinary business.industry medicine.medical_treatment Granulation tissue Inflammation 01 natural sciences Group A 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure 010608 biotechnology Platelet-rich plasma Edema medicine Skin grafting Animal Science and Zoology medicine.symptom Fibroblast business Wound healing |
| Zdroj: | Indian Journal of Animal Research. |
| ISSN: | 0976-0555 0367-6722 |
| DOI: | 10.18805/ijar.b-847 |
| Popis: | The present study compared the efficacy of autologous and homologous platelet rich plasma (PRP) as a surgical wound healing promoter in rabbits. Sixteen adult healthy rabbits were divided into two groups i.e. A and B. Group A was treated with autologous platelet rich plasma (APRP) and group B was treated with homologous platelet rich plasma (HPRP). Both groups were operated for skin grafting (auto grafting) at two (PRP treated experimental and control) sites. Clinical evaluation of PRP was performed by using macroscopic (edema, exudation, coloration, temperature, cosmetic appearance and healing status) and microscopic (acute inflammation, fibroblast proliferation and granulation tissue proliferation) parameters. The healing status, coloration and cosmetic appearance of APRP treated group were more satisfactory than HPRP treated group. APRP group also showed less inflammation, edema and more granular tissue proliferation as compare to HPRP group. It was concluded that autologous PRP is an efficient surgical wound healing promoter in rabbits. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|