Diarrea asociada a Clostridium difficile
| Autor: | Ángel Cosme, Luis Bujanda |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Enterocolitis
medicine.medical_specialty Hepatology medicine.diagnostic_test business.industry medicine.medical_treatment Gastroenterology Colonoscopy Clostridium difficile medicine.disease_cause Diarrhea Metronidazole Internal medicine Superinfection medicine Vancomycin medicine.symptom Intensive care medicine business medicine.drug Colectomy |
| Zdroj: | Gastroenterología y Hepatología. 32:48-56 |
| ISSN: | 0210-5705 |
| Popis: | Clostridium difficile is the most frequent cause of nosocomial diarrhea and is a significant cause of morbidity among hospitalized patients. The inflammation is produced as a result of a non-specific response to toxins. In the last few years, a hypervirulent strain, NAP1/BI/027, has been reported. Symptoms usually consist of abdominal pain and diarrhea. The diagnosis should be suspected in any patient who develops diarrhea during antibiotic therapy or 6-8 weeks after treatment. Diagnosis should be confirmed by the detection of CD toxin in stool and by colonoscopy in special situations. The treatment of choice is metronidazole or vancomycin. In some patients who do not respond to this therapy or who have complications, subtotal colectomy may be required. Relapse is frequent and must be distinguished from reinfection. Prevention and control in healthcare settings requires careful attention. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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