Relative specificity for active inflammatory bowel disease of plasma-derived proteins in gut lavage fluid
| Autor: | W. Gordon Brydon, Anne Ferguson, C. P. Choudari |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
medicine.medical_specialty
Hepatology biology business.industry Plasma derived digestive oral and skin physiology Gastroenterology Albumin Plasma leakage medicine.disease Ulcerative colitis Inflammatory bowel disease Internal medicine Immunology biology.protein medicine Lavage fluid Antibody business Perfusion |
| Zdroj: | European Journal of Gastroenterology & Hepatology. 5:269-274 |
| ISSN: | 0954-691X |
| DOI: | 10.1097/00042737-199304000-00013 |
| Popis: | Objective: Whole gut lavage with isotonic non-absorbable fluid is essentially a whole gut perfusion; whole gut lavage fluid (WGLF) can be used for clinical evaluation of intestinal immunity. High concentrations of WGLF immunoglobulin (Ig) G, albumin and α-1-antitripsin (A1AT; probably reflecting plasma leakage) are characteristics of active inflammatory bowel disease. We aimed to establish reference values for concentrations of these proteins in WGLF and to assess the extent of high concentrations in conditions other than active inflammatory bowel disease. Methods: Gut lavage was performed on 63 immunologically normal patients or volunteers and on 254 occasions in patients with gastrointestinal symptoms or disease |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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