Prevalence of hypovitaminosis D in patients with juvenile osteochondritis dissecans
| Autor: | V. Allende, M. Sanchez Ortiz, J. J. Masquijo, V. Oberti |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Vitamin
medicine.medical_specialty business.industry Incidence (epidemiology) Osteoarthritis medicine.disease Gastroenterology vitamin D deficiency Lesion chemistry.chemical_compound medicine.anatomical_structure chemistry Internal medicine Vitamin D and neurology Medicine Orthopedics and Sports Medicine Surgery In patient medicine.symptom Ankle business |
| Zdroj: | Revista Española de Cirugía Ortopédica y Traumatología (English Edition). 65:132-137 |
| ISSN: | 1988-8856 |
| DOI: | 10.1016/j.recote.2020.07.006 |
| Popis: | Background Juvenile osteochondritis dissecans (JOCD) is an acquired joint disease of unknown aetiology that affects skeletally immature patients and has the potential to progress to osteoarthritis. Recent studies have reported a high prevalence of vitamin D deficiency in patients with osteochondral lesions. The aim of our study was to determine serum vitamin D levels in patients diagnosed with JOCD. Methods Serum 25(OH)D levels of 31 patients (22 males) presenting 40 lesions (29 JOCD of the knee, and 11 of the ankle) were evaluated. The average age was 11.9 ± 2.9 years. Hypovitaminosis D was defined as a value less than 30 ng/ml and was divided into vitamin D insufficiency (20–30 ng/ml) and vitamin D deficiency ( Results Hypovitaminosis D was present in 45.2% of the evaluated patients (32.2% insufficiency and 13% deficiency). No significant differences were found in the mean values and incidence of hypovitaminosis between those patients in which the sample was taken in warm or cold season (P = .267 and P = .875, respectively). Patients who required surgery had a higher incidence of hypovitaminosis than those treated conservatively (60% versus 31%, P = .054). There was no correlation in the incidence of hypovitaminosis with sex, location, stability of the lesion, or if the lesion was uni or bilateral. Conclusion In our series, almost half of the patients diagnosed with JOCD presented abnormal serum levels of vitamin D. A two-fold incidence of hypovitaminosis was observed in patients requiring surgical treatment compared to patients managed conservatively. The association found in this study does not imply causation, but it should be considered within the set of actions for the treatment of these injuries. |
| Databáze: | OpenAIRE |
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