AB1216-HPR A Study of Possible Correlations of Sleep Disturbance with Disease Activity, Psychological State and Health Status in Patients with Rheumatoid Arthritis
| Autor: | M. Yukioka, Hajime Sano, C. Yukioka, N. Takai, Takashi Kuroiwa, T. Nakanishi, Yasushi Miura, K. Maeda, N. Murata, K. Higashi, T. Kuritani, M. Fusama, H. Nakahara, M. Inoue, T. Yukioka, K. Yukioka |
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| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Sleep disorder business.industry Immunology medicine.disease General Biochemistry Genetics and Molecular Biology Disease activity Pittsburgh Sleep Quality Index Rheumatology Internal medicine Rheumatoid arthritis Epidemiology medicine Physical therapy Immunology and Allergy Anxiety In patient medicine.symptom business Depression (differential diagnoses) |
| Zdroj: | Annals of the Rheumatic Diseases. 74:1341.2-1341 |
| ISSN: | 1468-2060 0003-4967 |
| DOI: | 10.1136/annrheumdis-2015-eular.4455 |
| Popis: | Background Sleep disturbance occasionally occurs in patients with rheumatoid arthritis (RA). It is not clear which factor mostly influences sleep disturbance in patients with RA. Objectives We evaluated which factors are correlated with sleep disturbance in patients with RA. Methods Patients with RA who met the 1987 revised criteria of ACR for RA or the 2010 ACR/EULAR classification criteria for RA were selected for this study. The levels of disease activity of RA was evaluated using swollen joint count (SJC), tender joint count (TJC), evaluator global assessment (EGA) and patient global assessment (PGA). Sleep disturbance was evaluated utilizing the Pittsburgh Sleep Quality Index (PSQI). Psychological factors were examined utilizing the Center for Epidemiological Studies Depression Scale (CES-D), the Hospital Anxiety and Depression Scale-Anxiety-Depression (HADS-D) and Anxiety (HADS-A) and the State-Trait Anxiety Inventory (STAI). Health status was evaluated with Short Form-36 (SF-36). We assessed the correlation of sleep disturbance with disease activity, psychological factors and health status. Data analyses were performed using Spearman correlation analysis. Results 112 patients with RA were recruited. Average of age: 54.8 years old, disease duration: 11.4 years, SJC: 2.7, TJC: 2.2, PGA: 23.2mm, EGA: 16.2mm. PSQI was not correlated with age, duration, SJC, TJC and EGA, while it was weakly statistically correlated with PGA (r=0.2592, p=0.0058). With regard to psychological state, PSQI was significantly correlated with CES-D (r=0.5165, p Conclusions Sleep disturbance was more strongly correlated with psychological state rather than disease activity and physical state. Psychological state is correlated with PGA [1] and PGA is reported to be a limiting factor for reaching remission of RA [2]. Addressing sleep disturbance symptoms may improve not only psychological state but also PGA, resulting in achievement of remission. References Fusama M, et al. Mod Rheumatol in press. Studenic P, et al. Ann Rheum Dis 2012; 71: 1702-5. Disclosure of Interest None declared |
| Databáze: | OpenAIRE |
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