Novel Route for the Construction of Chroman Ring System Using Cross-Coupling between Benzylic and Aliphatic Alcohols in the Presence of NaHSO4/SiO2

Autor:	Toshio Takido, Tadashi Aoyama, Mitsuo Kodomari, Takuya Furukawa, Mamiko Hayakawa
Rok vydání:	2015
Předmět:	Cascade reaction Chemistry Organic Chemistry Intramolecular cyclization Solid acid Ring (chemistry) Medicinal chemistry Coupling reaction
Zdroj:	Synlett. 26:1875-1879
ISSN:	1437-2096 0936-5214
DOI:	10.1055/s-0034-1380863
Popis:	Novel route for the construction of chromans from benzylic and aliphatic alcohols in the presence of NaHSO4/SiO2 has been developed. In this reaction, substituted olefins are formed from benzylic and aliphatic alcohols and then converted to chromans through intramolecular cyclization. Twenty novel chromans were synthesized by this simple procedure.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b6bd027a632a0a3dc3e51a2c9f9afe3a https://doi.org/10.1055/s-0034-1380863 Zobrazit plný text záznamu