The 2012 Surviving Sepsis Campaign: Management of Severe Sepsis and Septic Shock—An Update on the Guidelines for Initial Therapy

Autor: Timothy A. Albertson, Edward A. Panacek, Jeffrey P. Green, Jason Yeates Adams
Rok vydání: 2013
Předmět:
Zdroj: Current Emergency and Hospital Medicine Reports. 1:154-171
ISSN: 2167-4884
Popis: With the 2012 Surviving Sepsis Campaign Guidelines, clinicians have access to evidence based guidelines for the treatment of adults with severe sepsis. Some of the important changes include: new recommendations for screening of adults with sepsis for organ dysfunction (grade 1C); lactate normalization as a therapeutic target in early resuscitation (grade 2C); colloids no longer recommended for initial resuscitation (grade 1B); a minimum of 30 mL/kg for initial fluid resuscitation (grade 1C); norepinephrine as the initial vasopressor of choice (dopamine allowed only under specific circumstances) (grade 1B); removal of recombinant human activated protein C for the treatment of severe sepsis (ungraded); removal of permissive hypercapnea as a recommendation (ungraded); and a change of the target blood glucose level to
Databáze: OpenAIRE