The Effectiveness and Safety of Micropulse Cyclophotocoagulation in the Treatment of Ocular Hypertension and Glaucoma
| Autor: | Qayim Kaba, Eric S Tam, Darana Yuen, Sohel Somani |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Intraocular pressure
medicine.medical_specialty Visual acuity genetic structures business.industry 010102 general mathematics Ocular hypertension Glaucoma Retrospective cohort study General Medicine medicine.disease 01 natural sciences eye diseases 03 medical and health sciences 0302 clinical medicine Normal tension glaucoma Ophthalmology 030221 ophthalmology & optometry medicine In patient sense organs 0101 mathematics medicine.symptom Adverse effect business |
| Zdroj: | Ophthalmology Glaucoma. 3:181-189 |
| ISSN: | 2589-4196 |
| DOI: | 10.1016/j.ogla.2020.02.005 |
| Popis: | Purpose To evaluate the effectiveness and safety of primary and adjunctive micropulse cyclophotocoagulation (MPCPC) in the treatment of ocular hypertension (OHT) and glaucoma. Design Retrospective cohort study. Participants Ocular hypertension and all severities of glaucoma (including treatment-naive and well-sighted eyes) and all types of glaucoma (including normal-tension glaucoma [NTG]). Methods Consecutive eyes with glaucoma or OHT that underwent MPCPC (Iridex Cyclo G6 Glaucoma Laser System, Mountain View, CA) between 2016 and 2018 were identified. Main Outcome Measures Intraocular pressure (IOP), visual acuity, glaucoma medications, and ocular adverse events. Results Three hundred ninety-nine MPCPC surgeries, on 342 eyes of 214 patients, were analyzed. Laser power ranged from 900 to 2800 mW. Main diagnoses in descending prevalence were primary open-angle glaucoma (55.9%), chronic angle-closure glaucoma (10.8%), neovascular glaucoma (9.0%), NTG (6.5%), and OHT (5.5%). Mean baseline IOP was 19.8±7.4 mmHg and IOP reduction was 22.7%, 20.2%, 20.7%, and 23.7% at postoperative months (POMs) 1, 3, 6, and 12 (P Conclusions In patients with OHT or glaucoma, MPCPC demonstrated effectiveness and safety in IOP reduction sustained to 1 year. Baseline IOP of 21 mmHg or less subgroup demonstrated a more limited response. A dose-response relationship is suggested with respect to laser power and repeat treatments. |
| Databáze: | OpenAIRE |
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