| Autor: |
J.M. Burnell, E.A. Smuckler, R.A. Clift, Melvin B. Dennis, K.J. Clayson |
| Rok vydání: |
1976 |
| Předmět: |
|
| Zdroj: |
Gastroenterology. 71:827-831 |
| ISSN: |
0016-5085 |
| DOI: |
10.1016/s0016-5085(76)80368-x |
| Popis: |
The efficacy of cross-circulation in the treatment of acute liver failure has been evaluated in dogs. Four of 5 dogs administered a dose of yellow phosphorus that is lethal 90% of the time survived after treatment by cross-circulation of whole blood for between 1 and 8 hr with a normal dog. In 2 normal unmatched dogs plasma cross-circulations were performed over a period of 31 days without any clinical or laboratory manifestation of hypersensitivity except for lymphocytotoxic antibody titer rise. The results suggest that whole blood cross-circulation is effective and imply that a single donor could be utilized for prolonged periods of plasma cross-circulation with avoidance of immunological consequences of whole blood exchange. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
