Evaluation of Nurses’ and Patients’ Overall Satisfaction with New and Previous Formulations of Octreotide Long-acting Release (Sandostatin LAR®): A French Observational Study

Autor: Guillaume Cadiot, Denis Smith, Thierry Nguyen-Tan-Hon, Brigitte Delemer, F Schillo, Bénédicte Decoudier, Pierre-Luc Etienne, Romain Coriat, Alexandre Santos, Isabelle Raingeard, Ségolène Bisot-Locard, Iradj Sobhani, Gérald Raverot
Rok vydání: 2020
Předmět:
Zdroj: Advances in Therapy. 37:3901-3915
ISSN: 1865-8652
0741-238X
DOI: 10.1007/s12325-020-01429-4
Popis: The first long-acting release (LAR) formulation of octreotide was marketed in France in the late 1990s. An injectable formulation of Sandostatin LAR® (Novartis SAS) with a new diluent has been developed to facilitate its preparation and administration and to improve its use in practice. We conducted an observational, cross-sectional and multicenter study in France whose main outcome was to compare nurses’ satisfaction with the preparation and administration of both previous and new formulations of octreotide LAR. Secondary outcomes included assessment of patient satisfaction (quality of life and pain felt during the injection) and product tolerance. Data were collected at two time points (one for the first formulation group and one for the second formulation group) through paper questionnaires administered to physicians, patients and nurses including a visual analog scale (VAS) from 0 (unsatisfied) to 10 (very satisfied). Results showed that overall nurse satisfaction improved from 5.3 (95% CI 4.9–5.8) with the previous formulation to 7.5 (95% CI 7–7.9) with the new formulation (p
Databáze: OpenAIRE
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