On Intraocular Fibrinolysis

Autor: Inga Marie Nilsson, Maurizio Pandolfi, Jan‐Erik Niléhn
Rok vydání: 1966
Předmět:
Zdroj: Thrombosis and Haemostasis. 15:161-172
ISSN: 2567-689X
0340-6245
DOI: 10.1055/s-0038-1649419
Popis: Summary1. Intraocular fibrinolysis can be induced in rabbits by intravenous administration of streptokinase and plasminogen. Enhancement of intraocular fibrinolysis, however, requires a substantial increase in the fibrinolytic activity of the blood. Hence any attempt to induce therapeutic intraocular fibrinolysis by injection of fibrinolytic enzymes without checking the degree of fibrinolysis in the blood is meaningless.2. The blood-aqueous barrier did not show any significant change during fibrinolytic activation.3. Fibrinolytic split products could not be demonstrated in primary and plasmoid aqueous humour, but they were found in plasmoid aqueous after treatment of the animals with streptokinase and plasminogen.4. Intraocular fibrinolysis can be inhibited in primary and plasmoid aqueous by parenteral administration of ε-ACA.
Databáze: OpenAIRE