Regulatory Role of SGT1 in Early R Gene-Mediated Plant Defenses

Autor:	Paul Muskett, Jonathan D. G. Jones, Bart J. Feys, Mark J. Austin, Jane E. Parker, Katherine Kahn
Rok vydání:	2002
Předmět:	Genetics Multidisciplinary biology Gene interaction Arabidopsis biology.protein Arabidopsis thaliana R gene Plant disease resistance biology.organism_classification Gene Ubiquitin ligase Regulator gene
Zdroj:	Science. 295:2077-2080
ISSN:	1095-9203 0036-8075
Popis:	Animal SGT1 is a component of Skp1-Cullin–F-box protein (SCF) ubiquitin ligases that target regulatory proteins for degradation. Mutations in one ( SGT1b ) of two highly homologous Arabidopsis SGT1 genes disable early plant defenses conferred by multiple resistance ( R ) genes. Loss of SGT1b function in resistance is not compensated for by SGT1a . R genes differ in their requirements for SGT1b and a second resistance signaling gene, RAR1 , that was previously implicated as an SGT1 interactor. Moreover, SGT1b and RAR1 contribute additively to RPP5 -mediated pathogen recognition. These data imply both operationally distinct and cooperative functions of SGT1 and RAR1 in plant disease resistance.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b6222a02cea023aaee2a4b2687cd6507 https://doi.org/10.1126/science.1067747 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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