Vulvovaginal Candidiasis at Institute Pasteur of Dakar, Senegal: Prevalence and Associated Risk Factors

Autor: Cheikh Saad Bouh Boye, Philippe Dubrous, Chantal Mahou, Thierno Abdoulaye Diallo, Lauriane Koko Marcel Koumondji, Khadidiatou Mangou, Assane Dieng, Mame Diarra Diouf, Abdou Diop, Abdoulaye Seck, Khadim Diongue, Babacar Ndiaye
Rok vydání: 2022
Předmět:
Zdroj: Journal of Advances in Microbiology. :113-119
ISSN: 2456-7116
DOI: 10.9734/jamb/2022/v22i10670
Popis: Vulvovaginal candidiasis (CVV) is a superficial mycosis caused by Candida spp. with a predominance of C. albicans. CVV is opportunistic with several incriminated risk factors. This study aimed to determine the prevalence of CVV and to investigate potential risk factors. A cross-sectional study was carried out at the Medical Biology Laboratory in Pasteur Institute in Dakar, Senegal from September 1 to November 30, 2020. The study cohort was inclusive of all women received for a vaginal swab test in the laboratory unit. Each patient’s socio-demographic and clinical data were recorded before collecting two swabs samples for direct examination and culture on CHROMagar Candida incubated at 37 °C for 24 to 48 h. A total of 312 women with an average age of 32 years (range: 17-74) were included in this study. An overall CVV prevalence of 32% was found. C. albicans was predominant (73.2%) followed by C. glabrata (16.8%). The age group [30-40 years] was more infested with 35.3% (p = 0.434) as well as nulliparous or primiparous women with 38.7% (p = 0.171). CVV was more associated with disordered vaginal flora and pregnancy with 35.2% (p = 0.323) and 33.7% (p = 0.715) respectively. CVV was significantly related to contraception (p = 0.014). An overall high prevalence of CVV was observed mainly due to C. albicans. Contraception seems to be a factor contributing to its occurrence.
Databáze: OpenAIRE