Cleavage rate of mouse embryos in vivo and in vitro
Autor: | Anne McLaren, Patricia Bowman |
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Rok vydání: | 1970 |
Předmět: | |
Zdroj: | Development. 24:203-207 |
ISSN: | 1477-9129 0950-1991 |
DOI: | 10.1242/dev.24.1.203 |
Popis: | Mouse embryos (Q strain) developing in vivo from the 2-cell to the blastocyst stage showed a constant cell doubling time of about 10 h. Embryos cultured in vitro over the same period showed a rate of cleavage which was initially almost as great as in the reproductive tract, but subsequently declined to give a doubling time of about 24 h. Addition of oestrogen to the culture medium increased the diameter of blastocysts but did not increase cell number. |
Databáze: | OpenAIRE |
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