012 Outcomes following confirmed myocardial injury in patients with atrial fibrillation: a post hoc subgroup analysis of the high-STEACS trial
Autor: | Nicholas L. Mills, Tegan McKay, Kuan Ken Lee, Alasdair Gray, Benjamin Scally, Atul Anand |
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Rok vydání: | 2019 |
Předmět: |
Acute coronary syndrome
medicine.medical_specialty medicine.medical_treatment Population Subgroup analysis Critical Care and Intensive Care Medicine 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Sinus rhythm 030212 general & internal medicine education education.field_of_study biology business.industry Percutaneous coronary intervention 030208 emergency & critical care medicine Atrial fibrillation General Medicine Emergency department medicine.disease Troponin Emergency Medicine biology.protein Cardiology business |
Zdroj: | Emergency Medicine Journal. 36:777.3-778 |
ISSN: | 1472-0213 1472-0205 |
Popis: | Troponin rise in patients with atrial fibrillation may be falsely attributed to oxygen demand-supply mismatch rather than acute atherothrombotic events requiring urgent percutaneous coronary intervention. The purpose of this study was to compare the differences in clinical presentation, management and outcomes between patients in atrial fibrillation and sinus rhythm presenting to the Emergency Department with a suspected acute coronary syndrome. This is the first report to describe the atrial fibrillation patient population recruited to the High-STEACS trial.Patients recruited to theHigh-Sensitivity Troponin in the Evaluation of patients with suspected Acute Coronary Syndromes(High-STEACS) trial from three sites across South East Scotland with confirmed myocardial injury diagnosed by high-sensitivity cardiac troponin I were included in apost hocsubgroup analysis (n=3597). Baseline patient characteristics, coronary revascularisation treatment and one-year mortality outcomes were compared between individuals in atrial fibrillation and sinus rhythm.517 (14.4%) of patients presenting to Emergency Departments with confirmed myocardial injury were found to be in atrial fibrillation. One year all-cause mortality was higher in this population compared to patients presenting in sinus rhythm (24.8% vs 16.9%; p |
Databáze: | OpenAIRE |
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