A Retrospective Review of Bone Health Screening of at-risk Children and Adolescents: A Single Center Experience

Autor: Chun-cheung Antony Fu, Wing Hang Luk
Rok vydání: 2020
DOI: 10.21203/rs.3.rs-40556/v1
Popis: Background Bone health surveillance that includes laboratory tests and dual-energy x-ray absorptiometry (DXA) for patients with conditions that predispose them to a higher risk of osteoporosis is recommended. This study aimed to review current practice of such surveillance in a local tertiary referral centre. Methods Retrospective review of clinical data of patients who underwent DXA from 2013 to 2017 inclusive. Laboratory test results and presence of osteoporotic risk which was defined as bone mineral density (BMD) Z-score -2 SD or less were documented.Results This review consisted of 112 patients, 58 boys and age ranged from 1.1 to 20.3 years. Most referrals for DXA came from the subspecialty of nephrology (56.3%). Vitamin D status was rarely evaluated in this cohort of patients, only 17.9% of subjects had their vitamin D level checked. Overall, osteoporotic risk was demonstrated in 37% of the subjects. Thalassaemia, other haematological diseases like chronic ITP, osteogenesis imperfecta and inflammatory bowel disease accounted for majority of cases with high risk of osteoporosis.Conclusion DXA is underutilized in this center. Bone health surveillance and protection should be strengthened.
Databáze: OpenAIRE