FDG-PET-positive ovarian thecoma with GLUT5 expression: Five cases
| Autor: | Yasunari Mizumoto, Hiroshi Fujiwara, Takeshi Obata, Jyunpei Iwadare, Mitsuhiro Nakamura, Yukiko Bono |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Fluorodeoxyglucose
medicine.medical_specialty medicine.diagnostic_test business.industry Obstetrics and Gynecology Magnetic resonance imaging Standardized uptake value medicine.disease 030218 nuclear medicine & medical imaging 03 medical and health sciences Ovarian tumor 0302 clinical medicine Thecoma Positron emission tomography 030220 oncology & carcinogenesis medicine Positron emission Radiology Ovarian cancer business medicine.drug |
| Zdroj: | Journal of Obstetrics and Gynaecology Research. 43:599-603 |
| ISSN: | 1341-8076 |
| DOI: | 10.1111/jog.13243 |
| Popis: | Positron emission tomography (PET) with fluorodeoxyglucose F18 (18 F-FDG) is useful for detecting malignancies, but benign lesions occasionally have false-positive 18 F-FDG uptake. Here, we report the cases of five postmenopausal women with solid ovarian tumors suspected to be ovarian cancer on magnetic resonance imaging and 18 F-FDG uptake. Mean age of the five patients was 57 years (range, 53-65 years). Average early standardized uptake value (SUV) of 18 F-FDG was 5.76 (range, 2.2-12.0) and delayed SUV was 6.56 (range, 2.4-13.8). In all five patients, frozen section diagnosis at surgery was thecoma, and bilateral salpingo-oophorectomy was performed. On immunohistochemistry, immunoreactive glucose transporter 5 (GLUT5) expression was detected in thecoma tissues. This case shows that thecoma sometimes has positive 18 F-FDG uptake on positron emission tomography-computed tomography (PET-CT), indicating the need for caution regarding false-positive PET-CT in patients with benign solid ovarian tumor. |
| Databáze: | OpenAIRE |
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