The Effect of Vitamin D Supplementation on Clinical Outcomes of Asthmatic Children with Vitamin D Insufficiency
| Autor: | Daem Roshani, Ramesh Rahehagh, Rama Naghshi Zaryan, Wesam Kooti, Shilan Mohamadi, Asadollah Fathallahpour, Sivan Ahmadi, Hajar Kashefi, Rasoul Nasiri Kalmarzi, Behzad Khalafi |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Vital capacity business.industry Endocrinology Diabetes and Metabolism Incidence (epidemiology) medicine.disease Gastroenterology Pulmonary function testing Asthmatic children 03 medical and health sciences FEV1/FVC ratio 030104 developmental biology 0302 clinical medicine Immune system 030228 respiratory system Internal medicine medicine Vitamin D and neurology Immunology and Allergy business Asthma |
| Zdroj: | Endocrine, Metabolic & Immune Disorders - Drug Targets. 20:149-155 |
| ISSN: | 1871-5303 |
| Popis: | Background: The extensive impacts of vitamin D on the immune system has gathered the attention of scholars in last years. In this regard, studies about vitamin D and incidence of asthma have showed various results. The aim of this study was to evaluate the effect of vitamin D supplements on clinical outcomes in asthmatic children with vitamin D insufficiency. Materials & Methods: This before-after interventional study was conducted on all asthmatic children who attended the Be'sat Hospital, Iran. Serum levels of 25(OH)D, asthma severity and pulmonary function tests before and after therapeutic prescription of vitamin D were evaluated. Serum levels of 25(OH)D were measured by enzyme-linked immunosorbent assay. Results: The mean age of the samples was 10.69±9.78 years and 39 subjects (57.4%) were male. The primary mean level of serum 25(OH)D (18.21±8.22, ng/mL) has significantly (p Conclusion: We can conclude that therapeutic prescription of vitamin D is very effective in improving the clinical status of asthmatic children. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|