Efficient Synthesis of N-Fmoc-Aminoalkoxy Pentafluorophenyl Carbonates: Application for the Synthesis of Oligopeptidyl Carbamates

Autor:	H. P. Hemantha, Vommina V. Sureshbabu
Rok vydání:	2009
Předmět:	Carbonyl chloride Carbamate esters Chemistry Organic Chemistry Mass spectrometry Solution phase Combinatorial chemistry High yielding
Zdroj:	Synthetic Communications. 39:3555-3566
ISSN:	1532-2432 0039-7911
DOI:	10.1080/00397910902790378
Popis:	N-Fmoc-β-Aminoalkoxy pentafluorophenyl carbonates have been synthesized through the reaction of N-Fmoc-β-aminoalkoxy carbonyl chloride with pentafluorophenol. The reaction was clean and high yielding, and the products have been fully characterized using infrared, NMR, and mass spectroscopy. Their utility as efficient building blocks for the preparation of N-Fmoc-oligopeptidyl carbamate esters and acids has been demonstrated. The method exemplifies a simple protocol for the efficient preparation of oligopeptidyl carbamates in solution phase.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b5d478560d58d06462936470a518ee47 https://doi.org/10.1080/00397910902790378 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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