Myocardial Systolic Velocities and Deformation Assessed by Speckle Tracking for Early Detection of Left Ventricular Dysfunction in Asymptomatic Patients with Severe Primary Mitral Regurgitation
| Autor: | Oana Aurelia Enescu, Guido Lanzzillo, F.E.S.C. Dragos Vinereanu M.D., Maria Florescu, Diana Crina Ciresica Mihaela Benea, Roxana Cristina Rimbas, F.E.S.C. Gheorghe Cerin M.D., Mircea Cinteza, Marco Diena |
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| Rok vydání: | 2011 |
| Předmět: |
Lv function
Mitral regurgitation medicine.medical_specialty Ejection fraction business.industry Early detection Asymptomatic Internal medicine Lv dysfunction medicine Cardiology Radiology Nuclear Medicine and imaging medicine.symptom Cardiology and Cardiovascular Medicine business Mitral valve surgery Subclinical infection |
| Zdroj: | Echocardiography. 29:326-333 |
| ISSN: | 0742-2822 |
| DOI: | 10.1111/j.1540-8175.2011.01563.x |
| Popis: | Aims In asymptomatic patients with severe primary mitral regurgitation (PMR), early detection of left ventricular (LV) dysfunction indicates the optimal timing of mitral valve surgery; however, normal ejection fraction (EF) and end-systolic diameter (ESD) can mask significant LV impairment. Methods We studied 28 asymptomatic patients (59 ± 13 years, 18 male) with severe PMR, EF > 60%, and ESD 10% (13 patients) and IB, with an EF reduction Results Patients with PMR had longitudinal dysfunction and decreased radial systolic deformation, by comparison with controls, although EF and ESD were similar. Subgroup IA had significantly lower S(TVI) , LS, and RS than IB (7.3 ± 0.9 vs 10.8 ± 1.5 m/s; -16.0 ± 4.2% vs -21.7 ± 2.1%; and 37.4 ± 2.5% vs 41.6 ± 2.4%; all p 10% (r(2) = 0.52, p Conclusion Myocardial systolic velocities as well as radial and longitudinal LV deformation assessed by speckle tracking can detect subclinical LV dysfunction and predict impaired postoperative LV function in asymptomatic patients with severe PMR. |
| Databáze: | OpenAIRE |
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