In Silico Design of Bacterial N-acetylglucosaminidase Inhibitors with Potential Antibacterial Activity

Autor:	Marjana Novič, Tihomir Tomašič, Marko Anderluh, Dušan Turk, Tjaša Tibaut, Sara Pintar, Janja Sluga, Gregor Bajc
Rok vydání:	2019
Předmět:	chemistry.chemical_classification Chemistry In silico biochemical phenomena metabolism and nutrition medicine.disease_cause Microbiology Enzyme Staphylococcus aureus hemic and lymphatic diseases N acetylglucosaminidase medicine bacteria Glycoside hydrolase Antibacterial activity Pathogen
Zdroj:	The 2nd Molecules Medicinal Chemistry Symposium (MMCS): Facing Novel Challenges in Drug Discovery.
DOI:	10.3390/proceedings2019022105
Popis:	Staphylococcus aureus is a widespread gram-positive pathogen in humans and animals. AutolysinE (AtlE) is an enzyme from S. aureus which belongs to the glycoside hydrolase 73 family. [...]
Databáze:	OpenAIRE
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