Profile of Non Alcoholic Fatty Liver Disease (NAFLD) In Healthy Young Adults

Autor: Vijendra Kirnake, SN Mahajan, Monika Nathani, Nitin Pawani
Rok vydání: 2016
Předmět:
Zdroj: IOSR Journal of Dental and Medical Sciences. 15:114-121
ISSN: 2279-0853
2279-0861
Popis: Aims and Objectives: 1) To Study Occurrence of Non Alcoholic Fatty Liver Disease in Healthy Young Adults. 2) To Study Profile of subjects with Non Alcoholic Fatty Liver Disease in Healthy Young Adults. Materials and Methods: Study Design: A cross sectional study. Sample Size: 550 cases. Data Collection: 24 months (October 2013 To September 2015) Written informed consent was taken from the subjects after explaining the nature of the evaluation to them. Each person was subjected to a thorough history and physical examination as per the proforma. Methodology: History of Alcohol consumption, Jaundice, Medication, Family history of risk factors was obtained. Blood pressure and anthropometric measurements of the subjects were taken and biochemical investigations like fasting plasma glucose, fasting lipid profile, AST (SGOT) & ALT (SGPT). Ultrasonography of abdomen was done to detect fatty changes in the liver, which was performed by a single experienced radiologist who was blind to the study. Results: Out of 550 subjects, 83(15.09%) had fatty liver. There was statistically significant difference in NAFLD and normal group in Non biochemical factors like blood pressure, BMI, Waist circumference, WHR and Family history of risk factors and Biochemical factors like Fasting plasma Glucose (FPG), SGPT, Total Cholesterol, Triglycerides, LDL, VLDL. Conclusion: The present study concludes that the occurrence of NAFLD in healthy young adults was 15.09%. There is strong strength of association in developing into fatty liver with factors such as Waist-Hip ratio, waist circumference, body mass index (BMI), SGPT, total cholesterol, Triglycerides, LDL and VLDL.
Databáze: OpenAIRE
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