Reversible Friedel-Crafts acylations of 3-alkyl-1-(phenylsulfonyl)pyrroles: Application to the synthesis of an ant trail pheromone

Autor:	P. G. Seybold, Dong Xiao, James H. Cook, Jeffrey A. Schreier, Daniel M. Ketcha
Rok vydání:	1996
Předmět:	chemistry.chemical_classification Stereochemistry education Organic Chemistry food and beverages Trail pheromone behavioral disciplines and activities Biochemistry ANT chemistry Drug Discovery Friedel–Crafts reaction health care economics and organizations Alkyl
Zdroj:	Tetrahedron Letters. 37:1523-1526
ISSN:	0040-4039
DOI:	10.1016/0040-4039(96)00098-6
Popis:	Friedel-Crafts acylations of 3-alkyl-1-(phenylsulfonyl)pyrroles appear to be kinetically favored at the adjacent C-2 position but rearrangement to the C-5 position can occur after prolonged reaction times. This reversible Friedel-Crafts methodology has been employed for the synthesis of the ant trail pheromone, methyl 4-methylpyrrole-2-carboxylate.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b5c30965b70a2438a30c9a1d2d036891 https://doi.org/10.1016/0040-4039(96)00098-6 Zobrazit plný text záznamu Full Text from ScienceDirect