The Effect of Vitamin D on Falls: A Systematic Review and Meta-Analysis
| Autor: | Mitra M. Fatourechi, Mohammad Hassan Murad, Rebecca J. Mullan, Jaime P. Almandoz, Hau Liu, Patricia J. Erwin, Nisrin O. Abu Elnour, Khalid B. Elamin, Donald D. Hensrud, Melanie A. Lane, Victor M. Montori, Mohamed B. Elamin, Aziz A. Alkatib |
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| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
business.industry Endocrinology Diabetes and Metabolism Biochemistry (medical) Clinical Biochemistry Poison control Context (language use) Odds ratio Biochemistry Confidence interval law.invention Endocrinology Randomized controlled trial law Internal medicine Meta-analysis Physical therapy Vitamin D and neurology Medicine business Risk assessment |
| Zdroj: | The Journal of Clinical Endocrinology & Metabolism. 96:2997-3006 |
| ISSN: | 1945-7197 0021-972X |
| DOI: | 10.1210/jc.2011-1193 |
| Popis: | Context: Vitamin D affects bone and muscle health and likely reduces the risk of falls in the elderly. Objective: The aim of this systematic review is to summarize the existing evidence on vitamin D use and the risk of falls. Data Sources: We searched electronic databases from inception through August 2010. Study Selection: Eligible studies were randomized controlled trials in which the intervention was vitamin D and the incidence of falls was reported. Data Extraction: Reviewers working in duplicate and independently extracted study characteristics, quality, and outcomes data. Data Synthesis: Odds ratio and associated 95% confidence interval were estimated from each study and pooled using the random effects model. Results: We found 26 eligible trials of moderate quality that enrolled 45,782 participants, the majority of which were elderly and female. Vitamin D use was associated with statistically significant reduction in the risk of falls (odds ratio for suffering at least one fall, 0.86; 95% confidence... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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