COVID-19 and pemphigus: A descriptive series of twelve cases

Autor: Zoubida Mehsas, Soukaina Sektaoui, Meriem Meziane, Nadia Ismaili, Leila Benzekri, Karima Senouci
Rok vydání: 2022
Předmět:
Zdroj: Our Dermatology Online. 13:148-151
ISSN: 2081-9390
Popis: Background: Patients with pemphigus receiving immunosuppressive therapy are considered at risk of developing severe forms of COVID-19. We aimed to analyze the clinical and evolutionary characteristics of COVID-19 infection in patients with pemphigus receiving general corticosteroid therapy by a retrospective descriptive study of twelve cases. Patients and Methods: We identified´ pemphigus cases that developed a COVID-19 infection. The data collected included the characteristics and treatment of pemphigus and the features and course of COVID-19 infection. Results: Twelve patients were followed at our department for pemphigus and a developed COVID-19 infection. Nine patients had a severe form of pemphigus, and three were in clinical remission. The infection was severe in three patients. The evolution was good in all patients. Discussion: Our study suggests that systemic corticosteroid therapy in patients with severe forms of pemphigus may be a protective factor against severe forms of SARS-CoV-2 infection. This theory should be evaluated by a larger study.
Databáze: OpenAIRE