Supported liquid membrane extraction of urinarytrans, trans-muconic acid, a biomarker for benzene exposure

Autor:	Jan Norberg, Jan Åke Jönsson, Degu Tiruye, Lennart Mathiasson
Rok vydání:	2002
Předmět:	Detection limit chemistry.chemical_compound Muconic acid Analyte Chromatography chemistry Metabolite Ion chromatography Extraction (chemistry) Filtration and Separation Sample preparation Benzene Analytical Chemistry
Zdroj:	Journal of Separation Science. 25:351-355
ISSN:	1615-9314 1615-9306
Popis:	In this study, sample preparation of urinary trans, trans-muconic acid (tt-MA), a minor metabolite and biomarker of benzene, by means of Supported Liquid Membrane (SLM) extraction has been investigated. The sample extract was automatically transferred on-line to an ion exchange chromatographic column and the analytes were detected using a photodiode array detector. Automation of the system was accomplished using a robotic sample preparation processor integrated into the chromatographic system. Detection limits calculated from the baseline noise was in the sub-ppb range, and quantification of tt-MA is safe down to 10 ppb.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b5a8949d9f8057f63503540819f6f684 https://doi.org/10.1002/1615-9314(20020401)25:5/6<351::aid-jssc351>3.0.co Zobrazit plný text záznamu Plný text