PSMB4 Degrades the Porcine Reproductive and Respiratory Syndrome Virus Nsp1α Protein via the Autolysosome Pathway and Induces the Production of Type I Interferon

Autor: Heyou Yi, Qiumei Wang, Lechen Lu, Ruirui Ye, Ermin Xie, Zhiqing Yu, Yankuo Sun, Yao Chen, Mengkai Cai, Yingwu Qiu, Qianwen Wu, Jie Peng, Heng Wang, Guihong Zhang
Rok vydání: 2023
Předmět:
Zdroj: Journal of Virology. 97
ISSN: 1098-5514
0022-538X
DOI: 10.1128/jvi.00264-23
Popis: In the swine industry, PRRSV is a continuous threat, and the current vaccines are not effective enough to block it. This study determined that PSMB4 plays an antiviral role against PRRSV.
Databáze: OpenAIRE