PSMB4 Degrades the Porcine Reproductive and Respiratory Syndrome Virus Nsp1α Protein via the Autolysosome Pathway and Induces the Production of Type I Interferon
Autor: | Heyou Yi, Qiumei Wang, Lechen Lu, Ruirui Ye, Ermin Xie, Zhiqing Yu, Yankuo Sun, Yao Chen, Mengkai Cai, Yingwu Qiu, Qianwen Wu, Jie Peng, Heng Wang, Guihong Zhang |
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Rok vydání: | 2023 |
Předmět: | |
Zdroj: | Journal of Virology. 97 |
ISSN: | 1098-5514 0022-538X |
DOI: | 10.1128/jvi.00264-23 |
Popis: | In the swine industry, PRRSV is a continuous threat, and the current vaccines are not effective enough to block it. This study determined that PSMB4 plays an antiviral role against PRRSV. |
Databáze: | OpenAIRE |
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