Fluorinated Aliphatic Diazirines: Preparation, Characterization, and Photolabeling Studies

Autor: Urii Kornii, Oleg Shablykin, Taras Tarasiuk, Oleksandr Stepaniuk, Vitaliy Matvienko, Danylo Aloshyn, Nataliia Zahorodniuk, Pavel Mykhailiuk
Rok vydání: 2022
Popis: The previously unknown difluoromethyl- and the previously neglected trifluoromethyl-aliphatic diazirines were synthesized and characterized. Model photolabeling experiments and biological studies revealed that the stable trifluoromethyl-aliphatic diazirines could indeed be safely used as photoaffinity labels, while the labile difluoromethylated analogues - could not.
Databáze: OpenAIRE