Fluorinated Aliphatic Diazirines: Preparation, Characterization, and Photolabeling Studies
Autor: | Urii Kornii, Oleg Shablykin, Taras Tarasiuk, Oleksandr Stepaniuk, Vitaliy Matvienko, Danylo Aloshyn, Nataliia Zahorodniuk, Pavel Mykhailiuk |
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Rok vydání: | 2022 |
Popis: | The previously unknown difluoromethyl- and the previously neglected trifluoromethyl-aliphatic diazirines were synthesized and characterized. Model photolabeling experiments and biological studies revealed that the stable trifluoromethyl-aliphatic diazirines could indeed be safely used as photoaffinity labels, while the labile difluoromethylated analogues - could not. |
Databáze: | OpenAIRE |
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