| Autor: |
Ines Eisner-Janowicz, Randolph J. Nudo |
| Rok vydání: |
2006 |
| Předmět: |
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| Zdroj: |
Reprogramming the Cerebral Cortex |
| DOI: |
10.1093/acprof:oso/9780198528999.003.0012 |
| Popis: |
This chapter begins by reviewing the sequence of events that results in neuronal injury after stroke. It then reviews the advantages and disadvantages of various animal models used to model stroke and ischemic cortical injury. It considers the relationship of various aspects of behavioral assessment and the understanding of post-stroke plasticity and recovery. After a brief review of the organization of the motor cortex, the chapter reviews the evidence that neurophysiological and neuroanatomical plasticity occurs after cortical injury, emphasizing the role of postinjury behavior in the modulation of injury-induced changes. The cellular and synaptic basis for postinjury plasticity is briefly reviewed. Finally, the role of the intact hemisphere in recovery of function after unilateral cortical injury is discussed. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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