Reduced bacterial adhesion on titanium surfaces micro-structured by ultra-short pulsed laser ablation

Autor:	Nico S. Stumpp, Katharina Doll, Meike Stiesch, Elena Fadeeva, Boris N. Chichkov, Sebastian Grade
Rok vydání:	2016
Předmět:	chemistry technology industry and agriculture Biomedical Engineering chemistry.chemical_element Bioengineering Nanotechnology Adhesion Pulsed laser ablation Titanium Nanomaterials
Zdroj:	BioNanoMaterials. 17:53-57
ISSN:	2193-066X 2193-0651
DOI:	10.1515/bnm-2015-0024
Popis:	Implant-associated infections still pose serious problems in modern medicine. The development of fabrication processes to generate functional surfaces, which inhibit bacterial attachment, is of major importance. Sharklet™-like as well as grooves and grid micro-structures having similar dimensions were fabricated on the common implant material titanium by ultra-short pulsed laser ablation. Investigations on the biofilm formation of Staphylococcus aureus for up to 24 h revealed similarly reduced bacterial surface coverage on all micro-structures investigated compared to smooth titanium surfaces. This study is a prove-of-principle and could serve as basis for further investigations towards a structure-based biofilm-inhibiting implant.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b515216e460eae3c5a6f84823858caf0 https://doi.org/10.1515/bnm-2015-0024 Zobrazit plný text záznamu Plný text ve formátu PDF