Synthesis and Anti-Aggregation Activity of 2-[3-Methyl-1-Ethylxanth-8-Ylthio]Acetate Salts Containing Thietanyl and Dioxothietanyl Rings

Autor:	D. Z. Murataev, L. I. Bashirova, A. L. Urakov, F. A. Khaliullin, Konstantin G. Gurevich, Yu. V. Shabalina, F. Kh. Kamilov, A. V. Samorodov
Rok vydání:	2020
Předmět:	Pharmacology Diethylamine Diethanolamine Pharmacology toxicology Anti aggregation Cyclohexylamine Medicinal chemistry chemistry.chemical_compound Benzylamine chemistry Triethanolamine Drug Discovery medicine Piperidine medicine.drug
Zdroj:	Pharmaceutical Chemistry Journal. 54:444-448
ISSN:	1573-9031 0091-150X
DOI:	10.1007/s11094-020-02220-z
Popis:	Reactions of 2-[1-ethyl-3-methyl-7-(thietan-3-yl)- and 2-[1-ethyl-3-methyl-7-(1,1-dioxothietan-3-yl)xanth- 8-ylthio]acetic acids with amines (diethylamine, monoethanolamine, diethanolamine, triethanolamine, piperidine, cyclohexylamine, and benzylamine) gave 42 – 89% yields of 2-[1-ethyl-3-methyl-xanth-8-ylthio]- acetate salts containing thietanyl and dioxothietanyl rings. The structures of the synthesized compounds were confirmed using IR and PMR spectroscopy. The synthesized compounds exhibited anti-aggregation activity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b4e3f96445b16f2db34409fb3f542486 https://doi.org/10.1007/s11094-020-02220-z Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.