Clevidipine for hypertension treatment in pheochromocytoma surgery
| Autor: | L. Trillo-Urrutia, E. Arbonés-Aran, C. Luis-García, L. Lorente-Poch, C. Teixell-Aleu |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Insufflation
medicine.medical_specialty medicine.diagnostic_test business.industry Adrenalectomy medicine.medical_treatment 030209 endocrinology & metabolism Vasodilation General Medicine medicine.disease Surgery Pheochromocytoma 03 medical and health sciences 0302 clinical medicine Pneumoperitoneum 030202 anesthesiology medicine Laparoscopy business Perfusion Clevidipine medicine.drug |
| Zdroj: | Revista Española de Anestesiología y Reanimación (English Edition). 65:225-228 |
| ISSN: | 2341-1929 |
| Popis: | Pheochromocytoma is a catecholamine-producing tumour and laparoscopic adrenalectomy is its treatment of choice. During pneumoperitoneum insufflation and tumour handling there is a high risk of massive catecholamine release and hypertensive crisis. After tumour excision, severe arterial hypotension is a common effect, due to relative vasodilation and the residual effect of antihypertensive drugs. We report the case of a patient with pheochromocytoma who was treated with laparoscopic adrenalectomy. During surgical manipulation there was a sudden hypertensive peak that could be controlled quickly with clevidipine infusion. After tumour resection, clevidipine perfusion was stopped and there were no arterial hypotension episodes. Clevidipine is a new intravenous calcium antagonist with rapid onset of action and short half-life that has no residual effect and does not produce arterial hypotension after tumour resection. For these reasons, it can be a first-choice drug for this kind of surgery. |
| Databáze: | OpenAIRE |
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