| Autor: |
Runzhuo Sun, Yimiao Zeng, Yuanyuan Fan, Dan Lin, Siyu Du, Xiaoyu Wang |
| Rok vydání: |
2022 |
| DOI: |
10.21203/rs.3.rs-2000787/v1 |
| Popis: |
Background We aimed to assess the prognostic value of the combination of post-operative CEA and CA199 in patients with locally advanced rectal cancer (LARC) undergoing neoadjuvant chemoradiotherapy followed by TME. Methods Combined serum tumor biomarkers (CSTB) score were defined: Score 0: post-operative CEA 2.550 and post-operative CA199 > 16.36. Score 1: Other situations. The clinical outcome were overall survival (OS) and disease-free survival (DFS). Results According to multivariate analysis, for OS, only post-operative CA199 score were prognostic predictors, while post-operative CEA was not. For DFS, only CSTB score and perineural invasion were prognosis predictors. Conclusion This research revealed the novel scoring system combining postoperative CEA and CA199 had better prognostic value than those two index alone. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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