Factors Associated With Uterine Endometrial Hyperplasia and Pyometra in Wild Canids: Implications for Fertility

Autor: Gerardo R. Camilo, Cheryl S. Asa, Martin Zordan, Anneke Moresco, Sarah Devery, Sally Boutelle, Karen L. Bauman
Rok vydání: 2013
Předmět:
Zdroj: Zoo Biology. 33:8-19
ISSN: 0733-3188
Popis: The ability to safely and effectively manage reproduction is central to the success of AZA captive‐breeding programs.Although the AZA Wildlife Contraception Center routinely monitors contraceptive safety, there have been no studies thatcomparetheeffectsofcontraceptiveusetoseparationofmalesfromfemales,theotheroptionforpreventingreproduction.WeusedretrospectivemedicalrecordsandpathologyreportssubmittedbyAZAandrelatedfacilitiesforthesevenAZA‐managedcanid species to assess rates of uterine pathology relative to female reproductive life histories. Our results showed that theprevalence of both pyometra and endometrial hyperplasia (EH) was associated not only with treatment with the two mostcommoncontraceptives(Suprelorin®andMGAimplants)butalsowiththenumberofyearsbarren(i.e.,notproducingalitterand not contracepted). Rates of pyometra and EH were especially high in African painted dogs and red wolves, but lowest inswiftandfennec foxes.Thenumberofyearsproducingalitterhad alow association,suggesting itcouldbeprotective againstuterine pathology. A more recently developed Suprelorin® protocol using Ovaban® to prevent the initial stimulation phase,followed by implant removal when reversal is desired, may be a safer contraceptive option. These results concerning therelationship between reproductive management and uterine health have important implications for AZA‐managed programs,since the unsustainability of many captive populations may be due at least in part to infertility. Managing a female’sreproductive lifespan to optimize or maintain fertility will require a reconsideration of how breeding recommendations areformulated. Zoo Biol. 33:8–19, 2014.
Databáze: OpenAIRE
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