Switchable hydroxysulfonyloxylation and defluorination–decarboxylation sulfonylation of gem-difluoroalkenes with sodium sulfinate via aerobic oxidation

Autor:	Dan Song, Jinling Zhong, Jiaji Zhao, Canzhan Zhuang, Hua Cao, Jiatong Lin, Xiang Liu
Rok vydání:	2021
Předmět:	chemistry.chemical_compound endocrine system diseases Chemistry Decarboxylation Sodium Organic Chemistry chemistry.chemical_element Molecular oxygen Oxidative phosphorylation Combinatorial chemistry Free-radical addition Sulfone
Zdroj:	Organic Chemistry Frontiers. 8:6220-6225
ISSN:	2052-4129
DOI:	10.1039/d1qo01005k
Popis:	A novel and attractive aerobic oxidative hydroxysulfonyloxylation of gem-difluoroalkenes with sodium sulfinate via free radical addition has been developed. In addition, successive defluorination–decarboxylation sulfonylation of gem-difluoroalkenes in the presence of Et3N·3HF is realized. These transformations present dual capacity of molecular oxygen and sodium sulfinate, furnishing difluoroalkyl sulfonates and sulfone derivatives under metal-free and mild conditions.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b4afcbdd61717a52fd6826b5518a5047 https://doi.org/10.1039/d1qo01005k Zobrazit plný text záznamu