Blood serum and liver phospholipids of rats with chronic choline—protein deficiency

Autor:	Sergeeva Kv
Rok vydání:	1975
Předmět:	medicine.medical_specialty Cirrhosis Fat content Phospholipid General Medicine Biology medicine.disease General Biochemistry Genetics and Molecular Biology chemistry.chemical_compound Endocrinology Blood serum chemistry Liver tissue Internal medicine medicine Choline Fatty infiltration
Zdroj:	Bulletin of Experimental Biology and Medicine. 79:644-646
ISSN:	1573-8221 0007-4888
DOI:	10.1007/bf00786419
Popis:	The phospholipid content in the blood serum and liver tissue was studied for a period of eight months in rats kept on a cirrhosis-inducing diet with a high fat content and deficient in protein and choline, in animals receiving the same diet but with the addition of choline, and in control rats. Depending on the duration of its administration, the cirrhosis-inducing diet led to fatty infiltration of the liver, fibrocysts, and cirrhosis. At all stages of the pathological process there was a marked decrease in the phospholipid content in the blood serum and liver. In rats with developed nodular cirrhosis a tendency was observed for the phospholipid level to rise, possible on account of “newly formed” liver tissue. Choline prevented the development of fatty infiltration but did not completely prevent the fall in the phospholipid concentration in the liver.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b49441a9b7bcc03924293b4e8cba7d91 https://doi.org/10.1007/bf00786419 Zobrazit plný text záznamu Full text from SpringerLink