| Autor: |
V. P. Whittaker |
| Rok vydání: |
1992 |
| Předmět: |
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| Zdroj: |
Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques ISBN: 9783034871464 |
| DOI: |
10.1007/978-3-0348-7144-0_8 |
| Popis: |
Cholinergic transmission can claim to be the first form of chemical neurotransmission to be investigated by pharmacological and electrophysiological methods and the first in which both the transmitter and its receptor have been isolated and characterized. One reason for this is that neuromuscular transmission is cholinergic and the neuromuscular junction (especially that of frogs) is a readily investigated synapse in which responses are recorded by a muscular twitch — something which can be appreciated by direct observation and which does not require sophisticated equipment. Another is that in the form of the electric organs of strongly electric fish Nature has provided a tissue embryologically derived from muscle and retaining its cholinergic innervation but in a much more profuse form and therefore ideal for work at the cellular and molecular level [1]. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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