Palladium-catalyzed dehydrogenative annulation of imidazo[1,2- a ]pyridines with diarylalkynes

Autor:	Monoranjan Ghosh, Subhajit Mishra, Alakananda Hajra, Aswini Naskar
Rok vydání:	2015
Předmět:	Annulation chemistry.chemical_compound chemistry Organic Chemistry Drug Discovery Pyridine chemistry.chemical_element Indene Biochemistry Combinatorial chemistry Catalysis Palladium
Zdroj:	Tetrahedron Letters. 56:4101-4104
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2015.05.028
Popis:	Palladium-catalyzed direct dehydrogenative annulation of imidazo[1,2-a]pyridines with diarylalkynes through dual cleavage of C–H bonds has been developed. This new strategy offers a straightforward route for the synthesis of π-conjugated polyaromatic heterocycles from readily accessible imidazo[1,2-a]pyridine. An array of 2,3,4-triarylphenyl-1,7b-diaza-cyclopenta[cd]indene derivatives with broad functionalities are obtained in high yields by this protocol.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b48d26e68a1f3af2216ec490f52e0224 https://doi.org/10.1016/j.tetlet.2015.05.028 Zobrazit plný text záznamu Full Text from ScienceDirect