Perforator and Axial Venous Insufficiency in Sickle Cell Disease Patients with and without Leg Ulceration

Autor:	Tracy Olivier, Jonathan S. Deitch, Anupama Nehra, Jeremy Weedon, Albert S. Braverman, Thomas Raftery, Peter Gillette, Olugbenga Olowokure, Irina Belyayeva
Rok vydání:	2008
Předmět:	body regions medicine.medical_specialty medicine.anatomical_structure business.industry Cell medicine Radiology Nuclear Medicine and imaging Disease Cardiology and Cardiovascular Medicine business digestive system diseases Surgery
Zdroj:	Journal for Vascular Ultrasound. 32:79-81
ISSN:	1544-3175 1544-3167
DOI:	10.1177/154431670803200203
Popis:	Chronic or recurrent leg ulceration occurs in at least 25% of patients with sickle cell disease (SSD). Conflicting data exist concerning the association between SSD leg ulcers and axial venous insufficiency. To determine whether the incidence of perforator vein insufficiency (PVI) is greater in the ulcerated legs of SSD patients than in those without ulcers, the legs of 46 SSD patients, 25 of whom had chronic ulceration and of 19 normal young adult volunteers, were investigated with color-flow venous duplex Doppler sonography. PVI was found in 25 of 37 ulcerated legs and in 14 of 55 nonulcerated legs of SSD patients. The difference was significant (odds ratio 6.2). PVI may contribute to leg ulceration in SSD disease.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b481a95657c3bb4d48b0388bf71dff33 https://doi.org/10.1177/154431670803200203 Zobrazit plný text záznamu