The Five Years Surveillance and Trends of Antibiotic Resistance in Some Common Gram Negative Bacteria at the Vietnam Military Hospital
| Autor: | Ha Thi Thu Van, Nguyen Thai Son, Hoang Xuan Quang, Vo Thi Bich Thuy |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Carbapenem
biology medicine.drug_class Pseudomonas aeruginosa business.industry Antibiotics Cephalosporin General Medicine Drug resistance biochemical phenomena metabolism and nutrition Acinetobacter bacterial infections and mycoses biology.organism_classification medicine.disease_cause Microbiology Antibiotic resistance Ampicillin medicine business medicine.drug |
| Zdroj: | Advances in Microbiology. 10:730-741 |
| ISSN: | 2165-3410 2165-3402 |
| DOI: | 10.4236/aim.2020.1012052 |
| Popis: | The study is to identify trends and levels of antibiotic resistance of some common Gram-negative strains over time. The samples were collected from Vietnam Military Hospital 103 between 2014 and 2019. A total of 405 Acinetobacter baumannii., 528 Pseudomonas aeruginosa, 741 Escherichia coli, and 352 Klebsiella pneumoniae strains were identified and antimicrobial susceptibility was by Vitek system and Etest method. The multi-drug resistance (MDR) was major proportion of four common bacteria. In particular, there is a tendency to shift from MDR to Extended drug resistance (XDR) or possibly Pan drug resistant (pPDR). A. baumannii had the highest level of antibiotic resistance, namely, carbapenem (61.5% - 82.5%) and cephalosporin (72.7% - 88.7%). P. aeruginosa resisted most of commonly antibiotics, ranging from 50% to 70%. E. coli had a high resistance with antibiotics like ampicillin (87.2% - 97.6%) and the 3rd generation cephalosporins (up to 79.6%). K. pneumoniae resisted carbapenem from 14.7% to 44.4%, and other antibiotics with the higher rate of 40%. The collected data will be a prerequisite for further studies on mechanisms and factors related to antibiotic resistant bacteria, in order to find out a rational and effective using strategy of antibiotics. |
| Databáze: | OpenAIRE |
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