| Autor: |
G. O. Akintunde, Oyekunle, O E Adeleye, A. A. Adebiyi, A. O. Talabi, Abakpa S.A.V., M.E. Okandeji, F. M. Mshelbwala, O O Daramola, E S Ajibola |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Alexandria Journal of Veterinary Sciences. 64:123 |
| ISSN: |
1110-2047 |
| Popis: |
Summary: Animal African Trypanosomosis (AAT) is a devastating protozoan disease of animals and humans caused by Trypanosoma spp resulting in a great economic loss in the livestock industries, in the sub-sahara Africa. Cardiac troponin I is released from myocytes in both reversible and irreversible myocardial injuries. This study investigated the expression of cardiac troponin I (cTn I) in dogs experimentally infected with Trypanosoma congolense. Fifteen mongrel dogs of both sexes and with average body weights of 9.3 kg were divided into three groups (A, B and C). Dogs in group A were uninfected, group B were infected but untreated, while group C were infected and treated with Diminazene aceturate at a single dose of 3.5 mg/kg intramuscularly. The serum cTn I concentrations in infected dogs were elevated on days 1, 10 and 17 post-infection (pi). Serum cTn I concentrations in dogs that were infected and treated decreased on day 5 post-treatment (day 22 pi) compared to those that were infected but not treated. Post mortem and histopathological findings in the heart of a dogs that died of the disease in the infected but not treated group revealed no visible lesions. We concluded that the elevation of cTn I in Mongrel breed of dogs occurred without structural damage to cardiac muscles. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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