Popis: |
Three different membranes were tested for guided bone regeneration in 8-mm unicortical trephine defects in rabbit tibia. All experimental and control defects healed with bone. The critical size defect in rabbit tibia is larger than 8 mm, because control defects, 8 mm in diameter, healed spontaneously. Around remnants of the biodegradable Polyglactin 9 10 mesh (Vicryl®). a diffuse infiltration of inflammatory cells with multinuclear giant cells developed. However, the bone healing was not impaired by the infiltrate. Around the Gore-Tex® membrane and around remnants of the Alzamer® a few lymphocytes were observed, but no multinuclear giant 1 cells were noted. |