Obstructive Sleep Apnea in Children With Down Syndrome

Autor:	Carole L. Marcus, Thomas G. Keens, Daisy B. Bautista, Walter S. von Pechmann, Sally L. Davidson Ward
Rok vydání:	1991
Předmět:	Pediatrics Perinatology and Child Health respiratory tract diseases
Zdroj:	Pediatrics. 88:132-139
ISSN:	1098-4275 0031-4005
DOI:	10.1542/peds.88.1.132
Popis:	Children with Down syndrome have many predisposing factors for the obstructive sleep apnea syndrome (OSAS), yet the type and severity of OSAS in this population has not been characterized. Fifty-three subjects with Down syndrome (mean age 7.4 ± 1.2 [SE] years; range 2 weeks to 51 years) were studied. Chest wall movement, heart rate, electrooculogram, end-tidal Po2 and Pco2, transcutaneous Po2 and Pco2, and arterial oxygen saturation were measured during a daytime nap polysomnogram. Sixteen of these children also underwent overnight polysomnography. Nap polysomnograms were abnormal in 77% of children; 45% had obstructive sleep apnea (OSA), 4% had central apnea, and 6% had mixed apneas; 66% had hypoventilation (end-tidal Pco2, >45 mm Hg) and 32% desaturation (arterial oxygen saturation
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b4756c033f6ad091036a18891ca03d41 https://doi.org/10.1542/peds.88.1.132 Zobrazit plný text záznamu