Pharmacotherapeutic outcomes in atypical odontalgia: determinants of pain relief
| Autor: | Shiori Sugawara, Miho Takenoshita, Takeshi Watanabe, Yukiko Shinohara, Kaoru Kawasaki, Anna Miura, Yojiro Umezaki, Akira Toyofuku, Takayuki Suga, Trang T H Tu, Yuma Aota, Lou Mikuzuki |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
business.industry medicine.drug_class Atypical antipsychotic Atypical odontalgia Tricyclic antidepressant 03 medical and health sciences 0302 clinical medicine Anesthesiology and Pain Medicine Psychiatric history 030202 anesthesiology Internal medicine Toothache medicine Pain catastrophizing Aripiprazole medicine.symptom business 030217 neurology & neurosurgery Depression (differential diagnoses) medicine.drug |
| Zdroj: | Journal of Pain Research. 12:831-839 |
| ISSN: | 1178-7090 |
| DOI: | 10.2147/jpr.s188362 |
| Popis: | Objectives: There has been considerable research which has focused on clarifying the origin of pain in patients with atypical odontalgia (AO), also known as “idiopathic toothache”, and on identifying effective treatment, but there has been limited success so far. In this study, we assessed the outcomes of treatment and attempted to identify factors that could account for pain remission in patients with AO. Patients and methods: Data for 165 patients diagnosed with AO from June 2015 to August 2017 were retrospectively reviewed. The patients’ sex, age, duration of pain, and psychiatric history were collected, along with information on pain intensity, depressive status, and catastrophizing scores. Responses at 4 and 16 weeks from the start of treatment were observed. The associations between potentially associated factors and outcome were investigated using Bayesian model averaging. Results: A 30% reduction in pain was reported by 38 patients (46.3%) at 4 weeks and by 54 patients (65.9%) at 16 weeks. The pain intensity decreased as the depression and catastrophizing score improved; all of the changes were statistically significant (P |
| Databáze: | OpenAIRE |
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