Viral load and lymphocyte subpopulations in newly diagnosed patients with chronic Hepatitis B

Autor:	Snejina Mihailova, Valentina K Atanasova, Diana Petrova, Atanaska I Georgieva, Anastasiya Mihaylova, Marta Baleva, Georgi T. Popov, Naumova Elissaveta
Rok vydání:	2015
Předmět:	Hepatitis B virus Cellular immunity Immunophenotyping Immune system Immunology medicine Cytotoxic T cell CD38 Biology medicine.disease_cause Viral load Virology CD8
Zdroj:	Scripta Scientifica Medica. 47:65
ISSN:	1314-6408 0582-3250
DOI:	10.14748/ssm.v47i3.1238
Popis:	INTRODUCTION: The immune response against Hepatitis B virus (HBV) represents a key factor for infection outcome. However, the relation between viral replication and host immune reactivity is still a matter of investigation. AIM: To investigate whether the cellular immune response of newly diagnosed treatment naA¯ve chronic hepatitis B (CHB) patients may be influenced by the replicative status of HBV. MATERIALS AND METHODS: A total of 45 (17 female and 28 male) newly diagnosed untreated CHB patients aged 42.48±13.19 years (19A·71 years) were enrolled in this study. The patients were divided in two groups according to the viral load: >0A·â‰¤10 4 copies/ml (n=25) and >10 4 A·
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b45862f20b2e6b81dbb78ca633caf410 https://doi.org/10.14748/ssm.v47i3.1238 Zobrazit plný text záznamu