A case of invasive pulmonary aspergillosis diagnosed by transbronchial lung biopsy during treatment for diabetic ketoacidosis in a type 1 diabetic patient
| Autor: | Yumie Yamanaka, Ayu Kiritani, Chiaki Hosoda, Yoshitaka Seki, Kazuyoshi Kuwano, Naoaki Watanabe, Shota Fujimoto, Keisuke Saito, Ikumi Fujisaki, Hiroshi Takeda, Yasuhiko Endo, Akira Kinoshita, Hanae Miyagawa |
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| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Microbiology (medical) medicine.medical_specialty Diabetic ketoacidosis Combination therapy 030106 microbiology Malignancy 03 medical and health sciences 0302 clinical medicine Bronchoscopy Internal medicine medicine Pharmacology (medical) 030212 general & internal medicine skin and connective tissue diseases Voriconazole Type 1 diabetes medicine.diagnostic_test business.industry Micafungin Cancer bacterial infections and mycoses medicine.disease respiratory tract diseases Infectious Diseases business medicine.drug |
| Zdroj: | Journal of Infection and Chemotherapy. 26:274-278 |
| ISSN: | 1341-321X |
| Popis: | Invasive pulmonary aspergillosis (IPA) patients with non-hematological malignancy are far less than with hematological malignancy patients. We encountered a very rare case of IPA in which type 1 diabetes was the only conceivable risk factor. Further, according to the diagnostic categories of the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) criteria for IPA, the frequency of proven diagnosis is very low. Here we report a proven IPA, which rapidly developed when the patient with type 1 diabetes was being treated for diabetic ketoacidosis, which was successfully treated with the combination therapy of voriconazole (VRCZ) and micafungin (MCFG), based on early diagnosis using bronchoscopy. |
| Databáze: | OpenAIRE |
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