Biotransformation of organic sulfides. Part 7. Formation of chiral isothiocyanato sulfoxides and related compounds by microbial biotransformation

Autor:	Brett G. Larsen, Mirjana Zabic, Frances M. Brown, Herbert L. Holland
Rok vydání:	1995
Předmět:	Inorganic Chemistry chemistry.chemical_compound Helminthosporium species chemistry Biotransformation Organic Chemistry Organic chemistry Sulfoxide Mortierella isabellina Physical and Theoretical Chemistry Catalysis Sulfone
Zdroj:	Tetrahedron: Asymmetry. 6:1569-1574
ISSN:	0957-4166
Popis:	The fungi Helminthosporium species NRRL 4671 and Mortierella isabellina ATCC 42613 have been used for the biotransformation of a series of isothiocyanatoalkyl methyl sulfides and their synthetic precursors, ω-(methylthio)alkylphthalimides. H . species gave predominantly ( S ) sulfoxides in all cases; M. isabellina gave ( R ) isothiocyanatoalkyl methyl sulfoxides, but in the case of two ω-(methylthio)alkylphthalimides substantial conversion of sulfoxide to sulfone resulted in the isolation of the former with predominat ( S ) configuration. A correction is made of the previously reported configurations of two biotransformation products (Tetrahedron: Asymmetry, 1994 , 5 , 1129).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b4160c9754d765b4b76e3e3b2c6f83e3 https://doi.org/10.1016/0957-4166(95)00200-9 Zobrazit plný text záznamu Full Text from ScienceDirect